Long Chen's birth mother, who deeply loves him and sells her jewelry to buy medicine for his recovery.

Long Chen's personal maid, loyal to him, responsible for taking care of his daily needs and gathering medicinal herbs as per his requests.

Shi Feng is a loyal friend to Long Chen, often standing up for him, being the only one in the imperial capital who treats him like a brother, and lent Long Chen his precious sword as a stake. In the Literature Hall, Shi Feng's appearance intimidated Zhou Yaoyang's followers, protecting Long Chen.

Li Hao often mocks and provokes Long Chen, sees him as an enemy, and was defeated by Long Chen in a duel on the life-and-death platform. Plans revenge through a life-and-death battle.

Zhou Yaoyang is the eldest son of the Barbarian Marquis, who once severely injured Long Chen on the arena and insulted him with words. Long Chen retaliated in the Literature Hall, breaking Zhou Yaoyang's fingers, making him look pathetic, intensifying their hostile relationship. In the Battle Technique Pavilion, Zhou Yaoyang unexpectedly helped Long Chen avoid punishment. In this chapter, Long Chen continues to torment Zhou Yaoyang with pills, making his life worse than death.

Master Yun Qi is the chairman of the Alchemist Guild, who took a liking to Long Chen after he exposed Guan Cheng's misconduct, and gave him apprentice qualification and several precious items.

Meng Qi is Long Chen's arranged fiancée, beautiful and talented, with the ability to command a second-grade magical beast lion eagle. She has complex feelings toward Long Chen, wanting to break off the engagement due to Long Chen's predicament but still considering Long Chen and his mother's feelings. Long Chen showed persistence during the break-up, hoping to pursue her again through cultivation.

The Seventh Prince confronted Long Chen but was intimidated by Long Chen's alchemist identity token and became fearful.

After resolving misunderstandings with Long Chen, Chu Yao sympathized with his experiences, and they became friends. She demonstrated battle techniques to him and established a deep trust relationship with him. In this chapter, Chu Yao warned Long Chen about the Fourth Prince's disguised identity and expressed anticipation for Long Chen's help in resolving the heterogeneous spiritual power in her dantian.

Ah Man used his body to block a whip for Long Chen during an attack, showing powerful physical defense ability, and became brothers with Long Chen. Long Chen provided him with sufficient food sources to help activate his cells. In this chapter, Long Chen discovered Ah Man's physique could automatically absorb spiritual qi and tried to teach him cultivation.